Chemical filter

Bisdisulizole disodium

Water-soluble UVA filter with a large molecule and low skin penetration. Australia allows 10%. No prominent current safety signal.

Bisdisulizole disodium is a water-soluble UVA filter (peak about 335 nm, mainly UVA2), chemically a dimer analogue of ensulizole. The large charged molecule is expected to stay on the skin surface.

Australia allows 10% in listed therapeutic sunscreens, matching the usual EU cap (as acid). It is not on the US OTC monograph. Current literature describes a good safety profile and no prominent endocrine or cancer signal.

Uncommon in mass-market Australian bottles, more often seen in European water-based or hybrid formulas.

Sources

Sunscreens with Bisdisulizole disodium

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